Hemostasis, Prothrombin Time Assays

Prothrombin Time Assays

Thromboplastin Reagent

Cat. No.	Item
5380	Thromboplastin Reagent, 200 tests, 10 x 4 mL
5381	Thromboplastin Reagent, 500 tests, 10 x 10 mL
5382	Thromboplastin Reagent, 1000 tests, 10 x 20 mL

Thromboplastin Reagent is prepared from rabbit brain tissue for use in automated, semi-automated and manual PT tests and assays for Factors II, V, VII and X. Reagent is lyophilized; reconstitute with water. Reconstituted stability is 7 days at 2-8°C. International Sensitivity Index (ISI) values are between 2.0 and 2.5.

Thromboplastin-MI Reagent Kits (with Diluent)

Cat. No.	Item
5271	Thromboplastin-MI Kit, 250 tests, 5 x 10 mL
5272	Thromboplastin-MI Kit, 500 tests, 10 x 10 mL
5273	Thromboplastin-MI Kit, 1000 tests, 10 x 20 mL
5274	Thromboplastin-MI Kit, 125 tests, 5 x 5 mL

With a mid-range ISI assignment between 1.55 and 1.85, Thromboplastin-MI provides the sensitivity for INR monitoring of stabilized anticoagulated patients, early therapy, and detection of factor deficiencies. To eliminate pipetting errors and water problems, a convenient add-a-vial diluent is included with Thromboplastin-MI kits.

Thromboplastin-LI Reagent Kit

Cat. No.	Item
5248	Thromboplastin-LI Kit, 250 tests, 10 x 5 mL
5249	Thromboplastin-LI Kit, 500 tests, 10 x 10 mL

Thromboplastin-LI is a stable liquid, ready for use. With a low ISI assignment less than 1.50, this reagent offers reliable sensitivity to liver disease, depression of Vitamin K dependent factors, and coumarin-induced coagulation, even in the presence of high-dose heparin therapy. Open reagent is stable 14 days at 2-8°C.

aPTT Assays

aPTT-SA Reagent with Soluble Ellagic Acid Activator

Cat. No.	Item
5388	aPTT-SA Reagent Kit, 250 tests Ellagic Acid Activated Reagent, 5 x 5 mL 0.025 M Calcium Chloride, 5 x 5 mL
5389	aPTT-SA Reagent Kit, 500 tests Ellagic Acid Activated Reagent, 5 x 10 mL 0.025 M Calcium Chloride, 5 x 10 mL
5387	aPTT-SA Reagent, 1000 tests, 10 x 10 mL
5386	0.025 M Calcium Chloride, 1000 tests, 10 x 10 mL

aPTT-SA Reagent uses a soluble ellagic acid activator to provide a more optically clear reagent, an important consideration for automated analyzers with sensitive photo-optical detectors. Ellagic acid reagents also offer excellent precision and sensitivity. aPTT-SA reagent is a stabilized liquid available in three convenient kit sizes.

aPTT-ES Reagent with Ellagic Acid Activator
(Extra-Sensitive)

Cat. No.	Item
5397	aPTT-ES Reagent Kit, 500 tests ES Ellagic Acid Activated Reagent, 5 x 10 mL 0.025 M Calcium Chloride, 5 x 10 mL
5396	aPTT-ES Reagent, 1000 tests, 10 x 10 mL
5386	0.025 M Calcium Chloride, 10 x 10 mL

aPTT-ES Reagent is an optically clear, stabilized liquid with a soluble ellagic acid activator. It's extra sensitive to heparin, lupus-like anticoagulants, and factor deficiencies.

Factor Deficient Substrates/Owren's Veronal Buffer

Congenital Factor Deficient Substrate Plasmas

Cat. No.	Item
5190	Factor II Deficient Substrate, 10 x 1 mL
5191	Factor V Deficient Substrate, 10 x 1 mL
5192	Factor VII Deficient Substrate, 10 x 1 mL
5193	Factor VIII Deficient Substrate, 10 x 1 mL
5194	Factor IX Deficient Substrate, 10 x 1 mL
5195	Factor X Deficient Substrate, 10 x 1 mL
5196	Factor XI Deficient Substrate, 10 x 1 mL
5197	Factor XII Deficient Substrate, 10 x 1 mL

For use in Factor Assays, these plasmas are obtained from human congenitally deficient donors (Factor II includes bovine plasma) and have less than 1% residual factor activity.

Owren's Veronal Buffer

Cat. No.	Item
5375	Owren's Veronal Buffer, 10 x 25 mL

Owren's Veronal Buffer is used as a diluent in preparing patient sample dilutions for Factor Assays and Fibrinogen Assays.

Fibrinogen and Thrombin Time Assays

Fibrinogen Assay Kit

Cat. No.	Item
5376	Fibrinogen Assay Kit, 100 tests Thrombin Reagent, 5 x 2 mL Fibrinogen Calibrator, 2 x 1 mL Owren's Veronal Buffer, 2 x 25 mL Fibrinogen Assay Graph Paper, 1 sheet
5374	Thrombin Reagent, 200 tests, 10 x 2 mL
5378	Thrombin Reagent, 500 tests, 10 x 5 mL
5379	Fibrinogen Calibrator, 10 x 1 mL
The Fibrinogen Assay kit is for automated, semi-automated and manual quantitation of fibrinogen in plasma. The kit uses a relatively high working concentration of thrombin (100 NIH units/mL) and low fibrinogen concentration to minimize effects of heparin and FDPs. Reagents and calibrator are also available as individual items.

Helena Thrombin Clotting Time (TCT) Reagent

Cat. No.	Item
5377	Thrombin Time Reagent, 250 tests, 10 x 5 mL
Helena's TCT assay uses a low concentration of thrombin (3 NIH units/mL) with undiluted plasma. It is sensitive to fibrinogen levels below 70 mg/dL. The reagent is ideal for automated, semi-automated and manual instruments.